Ketamine-assisted therapy (KAT) shows promise as a treatment for substance use disorder (SUD) through several mechanisms:
Neuroplasticity Enhancement: Ketamine fosters neuroplasticity, aiding in rewiring neural circuits involved in addiction and reducing relapse likelihood.
Craving Reduction: It may reduce cravings by altering brain chemistry and connectivity, making it easier for individuals to adhere to treatment plans.
Emotional Processing and Trauma Healing: KAT can help individuals address underlying emotional or traumatic issues contributing to substance use.
Mood Stabilization: Ketamine's rapid antidepressant effects can stabilize mood, reducing symptoms of depression and anxiety, which often accompany SUD.
Improved Therapy Engagement: Ketamine's dissociative effects can break entrenched thought patterns, enhancing therapeutic outcomes.
Motivation and Insight: It can increase self-awareness and motivation, supporting sustained recovery efforts.
Enhanced Therapy Outcomes: When combined with psychotherapy, ketamine can make therapeutic interventions more effective.